Tight junction properties change during epidermis development
نویسندگان
چکیده
منابع مشابه
Organization and formation of the tight junction system in human epidermis and cultured keratinocytes.
Occludin and several proteins of the claudin family have been identiried in simple epithelia and in endothelia as major and structure-determining transmembrane proteins clustered in the barrier-forming tight junctions (TJ), where they are associated with a variety of TJ plaque proteins, including protein ZO-1. To examine whether TJ also occur in the squamous stratified epithelium of the interfo...
متن کامل-related Tight Junction Events
The molecular mechanisms by which Ca 2 1 and metal ions interact with the binding sites that modulate the tight junctions (TJs) have not been fully described. Metal ions were used as probes of these sites in the frog urinary bladder. Basolateral Ca 2 1 withdrawal induces the opening of the TJs, a process that is abruptly terminated when Ca 2 1 is readmitted, and is followed by a complete recove...
متن کاملDifferential regulation of tight junction permeability during development of the retinal pigment epithelium.
The retinal pigment epithelium (RPE) is an epithelial region of the blood-brain barrier. During embryogenesis, permeability of the barrier gradually decreases. A culture model of RPE development revealed differences in how tight junctions regulate the paracellular diffusion of ionic and nonionic solutes (Ban Y and Rizzolo LJ. Mol Vis 3: 18, 1997). To examine these differences, the permeation of...
متن کاملThe kidney tight junction
The tight junction is an important subcellular organelle which plays a vital role in epithelial barrier function. Claudin, as the integral membrane component of tight junctions, creates a paracellular transport pathway for various ions to be reabsorbed by the kidneys. This review summarizes advances in claudin structure, function and pathophysiology in kidney diseases. Different claudin species...
متن کاملDifferential regulation of tight junction permeability during development of the retinal pigment epithelium
Ban, Yuriko, and Lawrence J. Rizzolo. Differential regulation of tight junction permeability during development of the retinal pigment epithelium. Am J Physiol Cell Physiol 279: C744–C750, 2000.—The retinal pigment epithelium (RPE) is an epithelial region of the blood-brain barrier. During embryogenesis, permeability of the barrier gradually decreases. A culture model of RPE development reveale...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2012
ISSN: 0906-6705
DOI: 10.1111/j.1600-0625.2012.01573.x